Seminar Series

Ageing, Brain and Cognition: Some results from the Cambridge Centre for Ageing & Neuroscience (CamCAN)

I will describe a range of results from neuroscientific investigation of approximately 700 people from 18-88 years of age in the CamCAN project (, including: 1) separating the effects of age on vascular vs neural components of the BOLD response by combining resting-state fMRI and MEG; 2) effects of white matter (measured from diffusion kurtosis imaging) on age-related changes in latency of evoked MEG responses, 3) state-dependent effects of age on fMRI connectivity across rest, sensorimotor-responding and movie-watching; and 4) structural equation modelling of the relationship between gray- and white-matter integrity, executive function, memory and age.